London did not have a fire brigade in 1666. Each London parish kept buckets, axes, fire hooks and ladders to fight fires. These were often stored in churches, and local people were supposed to work together to put out fires in their area.
Fire hooks were used to pull down buildings to create fire breaks which prevented fires from spreading. The hooks were long and heavy and several people were needed to use them.
Fire engine technology was basic. The City of London had several hand-pumped machines that squirted water but they were not very effective.